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Tubulin isotypes of <i>C. elegans</i> harness the mechanosensitivity of the lattice for microtubule luminal accessibility

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Nature Physics, Published online: 26 August 2025; doi:10.1038/s41567-025-02983-w

Proteins interact with both the exterior and interior of microtubules. Here the relationship between microtubule building blocks and the accessibility of the microtubule interior to proteins is clarified.