Skip to main content

Dynamics of supracellular keratin bundling and nuclear uncaging in stretched epithelia

Submitted by wwwadm on

Nature Physics, Published online: 27 July 2026; doi:10.1038/s41567-026-03371-8

Keratin intermediate filaments form a cage around the nucleus to protect it from stress. Now it is shown that under large deformations the filaments bundle and ultimately release the nucleus from its cage.