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A non-equilibrium model for ultrasensitive switching in bacterial flagellar motors

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Nature Physics, Published online: 07 January 2026; doi:10.1038/s41567-025-03125-y

Bacterial motors respond to chemical signals with high sensitivity to control cell swimming behaviour. However, the established model that describes how this sensitivity arises is an equilibrium model, which is inconsistent with experimental findings. A model is now proposed in which high sensitivity results from non-equilibrium mechanical interactions within the motor.